Analysis of Some Fibrate-Type Antihyperlipidemic Drugs by AMD

被引:0
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作者
Wojciech Markowski
Katarzyna L. Czapińska
Genowefa Misztal
Łukasz Komsta
机构
[1] Medical University Lublin,Department of Physical Chemistry
[2] Medical University Lublin,Department of Medicinal Chemistry
关键词
Computer simulation; Fibrates;
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摘要
Conditions have been established for separation of six fib rate drugs by automatic multiple development (AMD). The best system was selected by using results from systematic investigation of relationships between ÄM values and mobile-phase composition. The drugs were separated by multiple development on diol plates with tetra-hydrofuran-hexane as mobile phase. The results of multiple development analysis predicted by computer simulation were compared with experimental results.
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页码:260 / 266
页数:6
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