A nation-wide twin study of social cognition in schizophrenia spectrum disorders

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作者：
Cecilie K. Lemvigh
Birte Y. Glenthøj
Birgitte Fagerlund
机构：
[1] Copenhagen University Hospital – Mental Health Services CPH,Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) and Center for Neuropsychiatric Schizophrenia Research (CNSR), Mental Health Center, Glostrup
[2] University of Copenhagen,Department of Clinical Medicine, Faculty of Health and Medical Sciences
[3] University of Copenhagen,Department of Psychology, Faculty of Social Sciences
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Schizophrenia | / 8卷
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摘要：
We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ). All participants were recruited through the Danish registers. Patients showed several deficits in the ability to detect sarcasm. Impairments were also observed in the unaffected MZ co-twins, indicating that social cognitive deficits could be a genetic vulnerability indicator of the disease. Worse social cognition was associated with lower intelligence and higher levels of psychopathology in patients.
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