Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics

被引：0

作者：

T. A. Redchuk

N. V. Korotkevich

A. A. Kaberniuk

E. S. Oliinyk

A. Yu. Labyntsev

S. I. Romaniuk

D. V. Kolibo

V. A. Busol

S. V. Komisarenko

机构：

[1] National Academy of Sciences of Ukraine,Palladin Institute of Biochemistry

[2] National University of Bioresources and Nature Management of Ukraine,undefined

来源：

Cytology and Genetics | 2010年 / 44卷

关键词：

Tuberculosis; Antibody Level; Tuberculosis Infection; Bovine Viral Diarrhea Virus; Cattle Herd;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The antibody responses to the recombinant analogs of Mycobacterium bovis antigens rMPB63 and rMPB83, as well as to tuberculin PPD, were determined in 96 bovine blood serum specimens. A statistical approach based on the approximation with multiple Gaussian curves with Levenberg-Marquardt algorithm was proposed for analysis of the distribution of antibody levels to the studied antigens. The results demonstrate that the recombinant MPB63 and MPB83 antigens along with the traditionally used PPD are appropriate for designing the test kits for diagnosing bovine tuberculosis at a herd level.

引用

页码：280 / 285

页数：5

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