External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane

被引:0
|
作者
Milos Galic
Sangmoo Jeong
Feng-Chiao Tsai
Lydia-Marie Joubert
Yi I. Wu
Klaus M. Hahn
Yi Cui
Tobias Meyer
机构
[1] Stanford University,Department of Chemical and Systems Biology
[2] Stanford University,Department of Electrical Engineering
[3] Cell Sciences Imaging Facility,Department of Pharmacology
[4] Stanford University School of Medicine,Department of Materials Science and Engineering
[5] Lineberger Comprehensive Cancer Center,undefined
[6] University of North Carolina,undefined
[7] Stanford University,undefined
[8] Present address: Center for Cell Analysis and Modeling,undefined
[9] University of Conneticut Health Center,undefined
[10] 400 Farmington Avenue,undefined
[11] Cell and Genome Sciences Building,undefined
[12] Farmington,undefined
[13] Connecticut 06032,undefined
[14] USA,undefined
来源
Nature Cell Biology | 2012年 / 14卷
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摘要
N-BAR-domain-containing proteins regulate membrane dynamics, as they stabilize curved membrane topologies, but whether they primarily sense or generate curvature has remained unclear. Galic, Meyer and colleagues now report that N-BAR proteins accumulate at highly curved membrane areas.
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页码:874 / 881
页数:7
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