Electrochemical characterization of poly(3,4-ethylenedioxythiophene)/κ-carrageenan as a biocompatible conductive coat for biologic applications

Poly(3,4-ethylenedioxythiophene) (PEDOT) is synthesized through a micellar dispersion that allows incorporation of biomolecules into this conductive polymer layer. A PEDOTiK-carrageenan (κC) system was obtained by electrodeposition and it was compared with a standard PEDOT:sodium dodecyl sulfate electrode coat. The electrochemical behavior and the oxidation level after 1000 cycles were studied through cyclic voltammetry and μRaman spectroscopy. The oxidation ratio in the PEDOT increased while electrochemical activity decreased in both cases. Moreover, the PEDOT:κC system allowed the immobilization of the acetylcholinesterase enzyme, which retained its activity. The unique combination of properties is a key feature in the bioelectronics field.