Drosophila melanogaster neurofibromatosis-1: ROS, not Ras?

被引：0
|
作者：
James A Walker
André Bernards
机构：
[1] James A. Walker and André Bernards are at the Massachusetts General Hospital Center for Cancer Research,
[2] Boston,undefined
[3] Massachusetts 02129,undefined
[4] USA. abernard@helix.mgh.harvard.edu,undefined
来源：
Nature Genetics | 2007年 / 39卷
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摘要：
A new study suggests that manipulating the expression of a Drosophila melanogaster neurofibromatosis-1 ortholog affects organismal lifespan through protein kinase A–mediated regulation of mitochondrial respiration and reactive oxygen species production. These results provide a new and unexpected twist to the study of NF1 signaling.
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页码：443 / 445
页数：2
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