Genome-wide association study identifies 74 loci associated with educational attainment

被引：0

作者：

Aysu Okbay

Jonathan P. Beauchamp

Mark Alan Fontana

James J. Lee

Tune H. Pers

Cornelius A. Rietveld

Patrick Turley

Guo-Bo Chen

Valur Emilsson

S. Fleur W. Meddens

Sven Oskarsson

Joseph K. Pickrell

Kevin Thom

Pascal Timshel

Ronald de Vlaming

Abdel Abdellaoui

Tarunveer S. Ahluwalia

Jonas Bacelis

Clemens Baumbach

Gyda Bjornsdottir

Johannes H. Brandsma

Maria Pina Concas

Jaime Derringer

Nicholas A. Furlotte

Tessel E. Galesloot

Giorgia Girotto

Richa Gupta

Leanne M. Hall

Sarah E. Harris

Edith Hofer

Momoko Horikoshi

Jennifer E. Huffman

Kadri Kaasik

Ioanna P. Kalafati

Robert Karlsson

Augustine Kong

Jari Lahti

Sven J. van der Lee

Christiaan deLeeuw

Penelope A. Lind

Karl-Oskar Lindgren

Tian Liu

Massimo Mangino

Jonathan Marten

Evelin Mihailov

Michael B. Miller

Peter J. van der Most

Christopher Oldmeadow

Antony Payton

Natalia Pervjakova

机构：

[1] Erasmus School of Economics,Department of Applied Economics

[2] Erasmus University,Department of Epidemiology

[3] Erasmus Medical Center,Department of Economics

[4] Erasmus University Rotterdam Institute for Behavior and Biology,Department of Psychology

[5] Harvard University,Department of Epidemiology Research

[6] Center for Economic and Social Research,Department of Complex Trait Genetics

[7] University of Southern California,Department of Government

[8] University of Minnesota Twin Cities,Department of Economics

[9] Division of Endocrinology and Center for Basic and Translational Obesity Research,Department of Systems Biology

[10] Program in Medical and Population Genetics,Department of Biological Psychology

[11] Broad Institute of MIT and Harvard,Department of Obstetrics and Gynecology

[12] The Novo Nordisk Foundation Center for Basic Metabolic Research,Department of Cell Biology

[13] Section of Metabolic Genetics,Department of Medical

[14] University of Copenhagen,Department of Public Health

[15] Faculty of Health and Medical Sciences,Department of Cardiovascular Sciences

[16] Statens Serum Institut,Department of Neurology

[17] Queensland Brain Institute,Department of Medical Epidemiology and Biostatistics

[18] The University of Queensland,Department of Twin Research and Genetic Epidemiology

[19] Icelandic Heart Association,Department of Epidemiology

[20] Faculty of Pharmaceutical Sciences,Department of Health

[21] University of Iceland,Department of Medical Genetics

[22] VU University,Department Of Health Sciences

[23] Center for Neurogenomics and Cognitive Research,Division of Cancer Epidemiology and Genetics

[24] Amsterdam Business School,Department of Cardiology

[25] University of Amsterdam,Divisions of Genetics and Rheumatology, Department of Medicine

[26] Uppsala University,Department of Neurological Sciences

[27] New York Genome Center,Department of Epidemiology

[28] New York University,Department of Gastroenterology and Hepatology

[29] Center for Biological Sequence Analysis,Department of Behavioral Sciences

[30] Technical University of Denmark,Department of Psychology

[31] VU University Amsterdam,Nuffield Department of Population Health

[32] COPSAC,Department of Genetics, Division of Statistical Genomics

[33] Copenhagen Prospective Studies on Asthma in Childhood,Department of Genomics

[34] Herlev and Gentofte Hospital,Department of Psychiatry

[35] University of Copenhagen,Division of Applied Health Sciences

[36] Steno Diabetes Center,Departments of Neurology & Psychiatry

[37] Institute of Clinical Sciences,Department of Genes and Environment

[38] Sahlgrenska Academy,Department of Genomics of Common Disease

[39] Research Unit of Molecular Epidemiology,Department of Clinical Physiology

[40] Helmholtz Zentrum München,Department of Clinical Physiology

[41] German Research Center for Environmental Health,Department of Psychiatry and Behavioral Sciences

[42] Institute of Epidemiology II,Department of Internal Medicine

[43] Helmholtz Zentrum München,Department of Medicine

[44] German Research Center for Environmental Health,Department of Psychiatry

[45] deCODE Genetics/Amgen Inc.,Department of Neurology

[46] Erasmus Medical Center Rotterdam,Department of Economics

[47] Istituto di Ricerca Genetica e Biomedica U.O.S. di Sassari,Department of Psychiatry and Behavioral Sciences

[48] National Research Council of Italy,Department of Psychiatry and Behavioral Neuroscience

[49] Psychology,Department of Cardiovascular Science

[50] University of Illinois,Department of Geriatrics

来源：

Nature | 2016年 / 533卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A genome-wide association study in 293,723 individuals identifies 74 genetic variants associated with educational attainment, which, although only explaining a small proportion of the variation in educational attainment, highlights candidate genes and pathways for further study.

引用

页码：539 / 542

页数：3

共 50 条

[1] Genome-wide association study identifies 74 loci associated with educational attainment
Okbay, Aysu
Beauchamp, Jonathan P.
Fontana, Mark Alan
Lee, James J.
Pers, Tune H.
Rietveld, Cornelius A.
Turley, Patrick
Chen, Guo-Bo
Emilsson, Valur
Meddens, S. Fleur W.
Oskarsson, Sven
Pickrell, Joseph K.
Thom, Kevin
Timshel, Pascal
de Vlaming, Ronald
Abdellaoui, Abdel
Ahluwalia, Tarunveer S.
Bacelis, Jonas
Baumbach, Clemens
Bjornsdottir, Gyda
Brandsma, Johannes H.
Concas, Maria Pina
Derringer, Jaime
Furlotte, Nicholas A.
Galesloot, Tessel E.
Girotto, Giorgia
Gupta, Richa
Hall, Leanne M.
Harris, Sarah E.
Hofer, Edith
Horikoshi, Momoko
Huffman, Jennifer E.
Kaasik, Kadri
Kalafati, Ioanna P.
Karlsson, Robert
Kong, Augustine
Lahti, Jari
van der Lee, Sven J.
de Leeuw, Christiaan
Lind, Penelope A.
Lindgren, Karl-Oskar
Liu, Tian
Mangino, Massimo
Marten, Jonathan
Mihailov, Evelin
Miller, Michael B.
van der Most, Peter J.
Oldmeadow, Christopher
Payton, Antony
Pervjakova, Natalia
NATURE, 2016, 533 (7604) : 539 - +
[2] Commentary: Genome-wide association study identifies 74 loci associated with educational attainment
Hernandez, Felix
Avila, Jesus
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2017, 10
[3] A Genome-Wide Association Study for Educational Attainment
Posthuma, D.
Willemsen, G.
van der Sluis, S.
Sullivan, P.
Smit, J. H.
Zandbelt, T.
de Geus, E. J. C.
Boomsma, D. I.
Penninx, B. W.
BEHAVIOR GENETICS, 2008, 38 (06) : 643 - 644
[4] Genome-Wide Association Study Identifies Loci Associated with Sensitive Skin
Farage, Miranda A.
Jiang, Yunxuan
Tiesman, Jay P.
Fontanillas, Pierre
Osborne, Rosemarie
COSMETICS, 2020, 7 (02)
[5] Genome-wide association study identifies novel loci associated with osteosarcoma
Savage, Sharon A.
Mirabelio, Lisa
Wang, Zhaoming
Gastier-Foster, Julie
Gorlick, Richard
Khanna, Chand
Flanagan, Adrienne M.
Tirabosco, Roberto
Andrulis, Irene L.
Wunder, Jay
Gokgoz, Nalan
Patino-Garcia, Ana
Sierrasesumaga, Luis
Lecanda, Fernando
Kurucu, Nilgun
Ilhan, Inci Ergurhan
Sari, Neriman
Serra, Massimo
Hattinger, Claudia
Picci, Piero
Spector, Logan
Barkauskas, Donald A.
Marina, Neyssa
de Toledo, Siliva Caminada
Petrilli, Sergio
Amary, Maria Fernanda
Halai, Dina
Thomas, David
Douglass, Chester
Meltzer, Paul
Jacobs, Kevin
Chung, Charles C.
Berndt, Sonja I.
Purdue, Mark P.
Caporaso, Neil E.
Tucker, Margaret
Rothman, Nathaniel
Landi, Maria Teresa
Silverman, Debra T.
Kraft, Peter
Hunter, David J.
Malats, Nuria
Kogevinas, Manolis
Wacholder, Sholom
Troisi, Rebecca
Helman, Lee
Fraumeni, Joseph F., Jr.
Yeager, Meredith
Hoover, Robert
Chanock, Stephen J.
CANCER RESEARCH, 2013, 73 (08)
[6] Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl, Eli A.
Breen, Gerome
Forstner, Andreas J.
McQuillin, Andrew
Ripke, Stephan
Trubetskoy, Vassily
Mattheisen, Manuel
Wang, Yunpeng
Coleman, Jonathan R. I.
Gaspar, Helena A.
de Leeuw, Christiaan A.
Steinberg, Stacy
Pavlides, Jennifer M. Whitehead
Trzaskowski, Maciej
Byrne, Enda M.
Pers, Tune H.
Holmans, Peter A.
Richards, Alexander L.
Abbott, Liam
Agerbo, Esben
Akil, Huda
Albani, Diego
Alliey-Rodriguez, Ney
Als, Thomas D.
Anjorin, Adebayo
Antilla, Verneri
Awasthi, Swapnil
Badner, Judith A.
Baekvad-Hansen, Marie
Barchas, Jack D.
Bass, Nicholas
Bauer, Michael
Belliveau, Richard
Bergen, Sarah E.
Pedersen, Carsten Bocker
Boen, Erlend
Boks, Marco P.
Boocock, James
Budde, Monika
Bunney, William
Burmeister, Margit
Bybjerg-Grauholm, Jonas
Byerley, William
Casas, Miquel
Cerrato, Felecia
Cervantes, Pablo
Chambert, Kimberly
Charney, Alexander W.
Chen, Danfeng
Churchhouse, Claire
NATURE GENETICS, 2019, 51 (05) : 793 - +
[7] Genome-Wide Association Study Identifies Genetic Loci Associated with Iron Deficiency
McLaren, Christine E.
Garner, Chad P.
Constantine, Clare C.
McLachlan, Stela
Vulpe, Chris D.
Snively, Beverly M.
Gordeuk, Victor R.
Nickerson, Debbie A.
Cook, James D.
Leiendecker-Foster, Catherine
Beckman, Kenneth B.
Eckfeldt, John H.
Barcellos, Lisa F.
Murray, Joseph A.
Adams, Paul C.
Acton, Ronald T.
Killeen, Anthony A.
McLaren, Gordon D.
PLOS ONE, 2011, 6 (03):
[8] Genome-wide association study identifies 30 loci associated with bipolar disorder
Eli A. Stahl
Gerome Breen
Andreas J. Forstner
Andrew McQuillin
Stephan Ripke
Vassily Trubetskoy
Manuel Mattheisen
Yunpeng Wang
Jonathan R. I. Coleman
Héléna A. Gaspar
Christiaan A. de Leeuw
Stacy Steinberg
Jennifer M. Whitehead Pavlides
Maciej Trzaskowski
Enda M. Byrne
Tune H. Pers
Peter A. Holmans
Alexander L. Richards
Liam Abbott
Esben Agerbo
Huda Akil
Diego Albani
Ney Alliey-Rodriguez
Thomas D. Als
Adebayo Anjorin
Verneri Antilla
Swapnil Awasthi
Judith A. Badner
Marie Bækvad-Hansen
Jack D. Barchas
Nicholas Bass
Michael Bauer
Richard Belliveau
Sarah E. Bergen
Carsten Bøcker Pedersen
Erlend Bøen
Marco P. Boks
James Boocock
Monika Budde
William Bunney
Margit Burmeister
Jonas Bybjerg-Grauholm
William Byerley
Miquel Casas
Felecia Cerrato
Pablo Cervantes
Kimberly Chambert
Alexander W. Charney
Danfeng Chen
Claire Churchhouse
Nature Genetics, 2019, 51 : 793 - 803
[9] A genome-wide association study identifies 41 loci associated with eicosanoid levels
Rhee, Eugene P.
Surapaneni, Aditya L.
Schlosser, Pascal
Alotaibi, Mona
Yang, Yueh-ning
Coresh, Josef
Jain, Mohit
Cheng, Susan
Yu, Bing
Grams, Morgan E.
COMMUNICATIONS BIOLOGY, 2023, 6 (01)
[10] Genome-wide association study identifies eight loci associated with blood pressure
Newton-Cheh, Christopher
Johnson, Toby
Gateva, Vesela
Tobin, Martin D.
Bochud, Murielle
Coin, Lachlan
Najjar, Samer S.
Zhao, Jing Hua
Heath, Simon C.
Eyheramendy, Susana
Papadakis, Konstantinos
Voight, Benjamin F.
Scott, Laura J.
Zhang, Feng
Farrall, Martin
Tanaka, Toshiko
Wallace, Chris
Chambers, John C.
Khaw, Kay-Tee
Nilsson, Peter
van der Harst, Pim
Polidoro, Silvia
Grobbee, Diederick E.
Onland-Moret, N. Charlotte
Bots, Michiel L.
Wain, Louise V.
Elliott, Katherine S.
Teumer, Alexander
Luan, Jian'an
Lucas, Gavin
Kuusisto, Johanna
Burton, Paul R.
Hadley, David
McArdle, Wendy L.
Brown, Morris
Dominiczak, Anna
Newhouse, Stephen J.
Samani, Nilesh J.
Webster, John
Zeggini, Eleftheria
Beckmann, Jacques S.
Bergmann, Sven
Lim, Noha
Song, Kijoung
Vollenweider, Peter
Waeber, Gerard
Waterworth, Dawn M.
Yuan, Xin
Groop, Leif
Orho-Melander, Marju
NATURE GENETICS, 2009, 41 (06) : 666 - 676

← 1 2 3 4 5 →