In Vitro Cutaneous Disposition of a Topical Diclofenac Lotion in Human Skin: Effect of a Multi-Dose Regimen

被引：0
|
作者：
Philip G. Hewitt
Nicholas Poblete
Ronald C. Wester
Howard I. Maibach
J. Zev Shainhouse
机构：
[1] University of California,Department of Dermatology
[2] San Francisco,undefined
[3] Surge Laboratory,undefined
[4] Department of Toxicology,undefined
[5] Dimethaid Research Inc.,undefined
来源：
Pharmaceutical Research | 1998年 / 15卷
关键词：
percutaneous absorption; diclofenac; multi-dose; human skin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. This study determines comparative bioavailability of diclofenac sodium lotion compared to an aqueous solution after topical application to viable human skin in vitro. In addition, the difference between a single dose and multiple doses (8 times) was also determined.
引用
收藏
页码：988 / 992
页数：4
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