Critical function of Prdm14 for the establishment of the germ cell lineage in mice

被引:0
|
作者
Masashi Yamaji
Yoshiyuki Seki
Kazuki Kurimoto
Yukihiro Yabuta
Mihoko Yuasa
Mayo Shigeta
Kaori Yamanaka
Yasuhide Ohinata
Mitinori Saitou
机构
[1] Laboratory for Mammalian Germ Cell Biology,
[2] Center for Developmental Biology,undefined
[3] RIKEN Kobe Institute,undefined
[4] 2-2-3 Minatojima-Minamimachi,undefined
[5] Laboratory of Molecular Cell Biology and Development,undefined
[6] Graduate School of Biostudies,undefined
[7] Kyoto University,undefined
[8] Yoshida-Konoe-cho,undefined
来源
Nature Genetics | 2008年 / 40卷
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学科分类号
摘要
Mitinori Saitou and colleagues report that Prdm14, which encodes a transcription factor expressed exclusively in the germ cell lineage, is essential for re-acquisition of pluripotency and epigenetic reprogramming of primordial germ cells.
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页码:1016 / 1022
页数:6
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