Pericentric inversion of chromosome 9 in infertile men

被引:32
|
作者
Sasagawa I. [1 ]
Ishigooka M. [1 ]
Kubota Y. [1 ]
Tomaru M. [1 ]
Hashimoto T. [1 ]
Nakada T. [1 ]
机构
[1] Department of Urology, Yamagata University, School of Medicine, Yamagata
关键词
Testosterone; Prolactin; Human Chorionic Gonadotropin; International Urology; Infertile Male;
D O I
10.1007/BF02550578
中图分类号
学科分类号
摘要
Reproductive condition was studied in 6 infertile men with pericentric inversion of chromosome 9. Semen analyses revealed one azoospermia, one oligozoospermia, three asthenozoospermias and one normozoospermia. Four cases showed normal levels of plasma gonadotropins and testosterone. The response of plasma testosterone to human chorionic gonadotropin was within the normal range in all cases. However, the administration of LH-RH resulted in abnormal response of plasma gonadotropin in all patients. These results indicate that infertile males with pericentric inversion of chromosome 9 have an abnormality in the hypothalamic-pituitary - testicular axis.
引用
收藏
页码:203 / 207
页数:4
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