Enhancement of Valsartan Dissolution Rate by the Increased Porosity of Pellets Using Supercritical CO2: Optimization via Central Composite Design

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作者
Abbas Akhgari
Fatemeh Nosrati
Pouria Rahmanian-Devin
Farzin Hadizadeh
Hossein Shahdadi Sardou
Hossein Kamali
机构
[1] Mashhad University of Medical Sciences,Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute
[2] Mashhad University of Medical Sciences,Department of Pharmaceutics, School of Pharmacy
[3] Mashhad University of Medical Sciences,Biotechnology Research Center, Pharmaceutical Technology Institute
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关键词
Valsartan; Pellet; Porosity; Enhancement dissolution; scCO;
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页码:861 / 873
页数:12
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