Hypertension, Blood Pressure Variability, and Target Organ Lesion

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作者
Maria-Cláudia Irigoyen
Kátia De Angelis
Fernando dos Santos
Daniela R. Dartora
Bruno Rodrigues
Fernanda Marciano Consolim-Colombo
机构
[1] University of Sao Paulo,Hypertension Unit, Heart Institute (InCor), School of Medicine
[2] Universidade Nove de Julho (UNINOVE),Laboratory of Translational Physiology
[3] Instituto de Cardiologia do Rio Grande do Sul/ Fundação Universitária de Cardiologia (IC/FUC),Faculty of Physical Education
[4] University of Campinas (UNICAMP),undefined
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关键词
Hypertension; Autonomic dysfunction; Blood pressure variability; Target-organ damage;
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摘要
Hypertensive patients have a higher risk of developing health complications, particularly cardiovascular (CV) events, than individuals with normal blood pressure (BP). Severity of complications depends on the magnitude of BP elevation and other CV risk factors associated with the target organ damage. Therefore, BP control and management of organ damage may contribute to reduce this risk. BP variability (BPV) has been considered a physiological marker of autonomic nervous system control and may be implicated in increased CV risk in hypertension. This review will present some evidence relating BPV and target organ damage in hypertension in clinical and experimental settings.
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