Role of renin-angiotensin system in the formation of emotional state in humans

被引：0
|
作者：
V. A. Shleptsova
N. V. Malyuchenko
M. A. Kulikova
M. A. Timofeeva
J. V. Shchegolkova
A. M. Vedjakov
O. V. Sysoeva
A. G. Tonevitsky
机构：
[1] M. V. Lomonosov Moscow State University,Department of Fundamental Medicine
[2] M. V. Lomonosov Moscow State University,Department of Biology
[3] All-Russian Institute of Physical Training and Sport,Institute of Higher Nervous Activity and Neurophysiology
[4] Russian Academy of Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2008年 / 145卷
关键词：
renin-angiotensin system; genetic polymorphism; angiotensin-converting enzyme; aggression;
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摘要：
We studied the effect of angiotensin-converting enzyme gene polymorphism on human emotional state in humans (189 athletes and 212 volunteers not engaged in sport activity). The distribution of angiotensin-converting enzyme genotypes was estimated. The dependence of aggression on age, sex, and professional activity was evaluated. This polymorphism was associated with physical aggression in female synchronized swimmers. Physical aggression in II genotype carriers was lower than in D allele carriers. Our results indicate that individual differences in aggression depend on professional activity and are genetically determined.
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