Streptococcus agalactiae Serotype Distribution and Antimicrobial Susceptibility in Pregnant Women in Gabon, Central Africa

被引：0

作者：

Sabine Belard

Nicole Toepfner

Mesküre Capan-Melser

Ghyslain Mombo-Ngoma

Rella Zoleko-Manego

Mirjam Groger

Pierre-Blaise Matsiegui

Selidji T. Agnandji

Ayôla A. Adegnika

Raquel González

Peter G. Kremsner

Clara Menendez

Michael Ramharter

Reinhard Berner

机构：

[1] Centre de Recherches Médicales de Lambaréné,Department of Pediatric Pneumology and Immunology

[2] Hôpital Albert Schweitzer,Department of Medicine I, Division of Infectious Diseases and Tropical Medicine

[3] Institut für Tropenmedizin,Département de Parasitologie

[4] Universität Tübingen,undefined

[5] Charité-Universitätsmedizin Berlin,undefined

[6] Clinic and Polyclinic for Pediatrics and Adolescent Medicine,undefined

[7] University Hospital Carl Gustav Carus,undefined

[8] Technische Universität Dresden,undefined

[9] Medical University of Vienna,undefined

[10] Université des Sciences de la Santé,undefined

[11] Ngounie Medical Research Centre,undefined

[12] ISGlobal,undefined

[13] Barcelona Ctr. Int. Health Res (CRESIB),undefined

[14] Hospital Clínic- Universitat de Barcelona),undefined

来源：

Scientific Reports | / 5卷

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摘要：

Neonatal invasive disease due to Streptococcus agalactiae is life threatening and preventive strategies suitable for resource limited settings are urgently needed. Protective coverage of vaccine candidates based on capsular epitopes will relate to local epidemiology of S. agalactiae serotypes and successful management of critical infections depends on timely therapy with effective antibiotics. This is the first report on serotype distribution and antimicrobial susceptibility of S. agalactiae in pregnant women from a Central African region. Serotypes V, III and Ib accounted for 88/109 (81%) serotypes and all isolates were susceptible to penicillin and clindamycin while 13% showed intermediate susceptibility to erythromycin.

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Toepfner, Nicole
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Zoleko-Manego, Rella
Groger, Mirjam
Matsiegui, Pierre-Blaise
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Adegnika, Ayola A.
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Kremsner, Peter G.
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Ramharter, Michael
Berner, Reinhard
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