Tumor-specific mutations in p53: The acid test

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作者
Pierre Hainaut
机构
[1] Molecular Carcinogenesis Group International Agency for Research on Cancer,
来源
Nature Medicine | 2002年 / 8卷
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摘要
Tumor-specific, 'signature' mutations of p53 have been identified in several cancers. The molecular basis of these tissue-specific selections has been poorly understood. A recent report sheds light on this issue by identifying the molecular basis of one such signature mutation found in adrenal cortical carcinomas.
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页码:21 / 23
页数:2
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