A Portrait of the Bcl-2 Protein Family: Life, Death, and the Whole Picture

被引:0
|
作者
Marc Pellegrini
Andreas Strasser
机构
[1] The Walter and Eliza Hall Institute of Medical Research,
来源
Journal of Clinical Immunology | 1999年 / 19卷
关键词
Bcl-2 family of proteins; apoptosis; cancer; autoimmunity; infection;
D O I
暂无
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学科分类号
摘要
The Bcl-2 family of proteins are important regulators of cell death. They are comprised of two opposing factions, the proapoptotic versus the antiapoptotic members. Both are required for normal development and cellular homeostasis of the immune system and other tissues. However, in certain circumstances they may participate in the development of disease.
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页码:365 / 377
页数:12
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