A Portrait of the Bcl-2 Protein Family: Life, Death, and the Whole Picture
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作者:
Marc Pellegrini
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机构:The Walter and Eliza Hall Institute of Medical Research,
Marc Pellegrini
Andreas Strasser
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机构:The Walter and Eliza Hall Institute of Medical Research,
Andreas Strasser
机构:
[1] The Walter and Eliza Hall Institute of Medical Research,
来源:
Journal of Clinical Immunology
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1999年
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19卷
关键词:
Bcl-2 family of proteins;
apoptosis;
cancer;
autoimmunity;
infection;
D O I:
暂无
中图分类号:
学科分类号:
摘要:
The Bcl-2 family of proteins are important regulators of cell death. They are comprised of two opposing factions, the proapoptotic versus the antiapoptotic members. Both are required for normal development and cellular homeostasis of the immune system and other tissues. However, in certain circumstances they may participate in the development of disease.
机构:
PO Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, AustraliaPO Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, Australia
Adams, JM
Cory, S
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机构:
PO Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, AustraliaPO Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, Australia
机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLANDIMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND
Moroy, T
Zornig, M
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机构:
IMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLANDIMPERIAL CANC RES FUND, BIOCHEM CELL NUCLEUS LAB, LONDON WC2A 3PX, ENGLAND