Molecular mechanisms of protein aggregation from global fitting of kinetic models

被引：0
|
作者：
Georg Meisl
Julius B Kirkegaard
Paolo Arosio
Thomas C T Michaels
Michele Vendruscolo
Christopher M Dobson
Sara Linse
Tuomas P J Knowles
机构：
[1] University of Cambridge,Department of Chemistry
[2] Lund University,Department of Biochemistry and Structural Biology
来源：
Nature Protocols | 2016年 / 11卷
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摘要：
Understanding the mechanism of amyloid formation (protein aggregation) is important for developing treatments for many neurodegenerative diseases. Amylofit is a program for determining mechanisms and rates from protein aggregation kinetics.
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页码：252 / 272
页数：20
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