Fractalkine receptor chemokine (CX3CR1) influences on cervical and lumbar disc herniation

被引：0
|
作者：
In-Soo Oh
Dong-Whan Suh
Sung-Ryeoll Park
Kee-Yong Ha
机构：
[1] The Catholic University of Korea,Department of Orthopaedic Surgery, Seoul St. Mary’s Hospital, College of Medicine
[2] The Catholic University of Korea,Departments of Orthopaedic Surgery, Incheon St. Mary’s Hospital
来源：
Indian Journal of Orthopaedics | 2015年 / 49卷
关键词：
Lumbar disc; fractalkine receptor; herniated nucleus pulposus; Lumbar; cervical; disc; herniated; receptors; chemokine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Herniation of nuclear or disc material along with, inflammatory chemokines such as prostaglandin E2, interleukin-6, matrix metalloproteinase and nitric oxide has definite correlation, possibly they are over produced. CX3CL1 and its receptor (CX3CR1) are part of chemokine system involved in leukocyte recruitment and adhesion in chronic inflammatory disease, but its role in spinal herniated nucleus pulposus (HNP) is unknown. We evaluated the expression of CX3CL1 and CX3CR1 in patients with disc herniation to clarify the role of CX3CL1 and CX3CR1 in the disc degeneration and to compare between cervical and lumbar HNP
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页码：239 / 244
页数：5
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