Alterations of leptin and ghrelin serum concentrations in renal disease: simple epiphenomena?

被引：0
|
作者：
Jörg Dötsch
Kai Nüsken
Michael Schroth
Wolfgang Rascher
Udo Meißner
机构：
[1] Friedrich-Alexander University Erlangen,Klinik für Kinder und Jugendliche
来源：
Pediatric Nephrology | 2005年 / 20卷
关键词：
Leptin; Ghrelin; Dialysis; Chronic renal failure; Appetite;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The hypothesis that alterations of serum concentrations of the anorexigenic adipose tissue-derived hormone leptin or the orexigenic peptide ghrelin might help to regain appetite and fight malnutrition in patients with chronic renal failure cannot be confirmed at present. For the future, however, strategies interfering with signal transduction of these peptides in the hypothalamus might be more promising and should be investigated and further developed.
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页码：701 / 706
页数：5
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