Changes in the physiological roles of neurotransmitters during individual development

被引:25
|
作者
Buznikov G.A. [1 ]
Shmukler Yu.B. [1 ]
Lauder J.M. [2 ]
机构
[1] N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, 26 Vavilov Street
[2] University of Northern Carolina, Chapel Hill
基金
俄罗斯基础研究基金会; 美国国家卫生研究院;
关键词
Embryogenesis; Morphogenesis; Neurogenesis; Neurotransmitters; Oocytes;
D O I
10.1007/BF02461353
中图分类号
学科分类号
摘要
The classical neurotransmitters (acetylcholine and biogenic monoamines) are multifunctional substances involved in intra- and intercellular signaling at all stages of ontogenesis in multicellular animals. A cyclical scheme is proposed to describe age-related changes in neurotransmitter functions at different stages of development from oocyte maturation to neuron formation. This may reflect not only the temporospatial organization of neurotransmitter processes, but also the origin of the functions of acetylcholine and biogenic monoamines from the protosynapses of the cleaved embryo to neuronal synapses. © 1999 Kluwer Academic/Plenum Publishers.
引用
收藏
页码:11 / 21
页数:10
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