New era for drug discovery and development in renal disease

被引：0
|
作者：
Toshio Miyata
Katsushi Kikuchi
Hideyasu Kiyomoto
Charles van Ypersele de Strihou
机构：
[1] United Centers for Advanced Research and Translational Medicine,
[2] Tohoku University Graduate School of Medicine,undefined
[3] Clinical Research Center of Tohoku University Hospital,undefined
[4] Service de Néphrologie,undefined
[5] Université Catholique de Louvain,undefined
来源：
Nature Reviews Nephrology | 2011年 / 7卷
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摘要：
The traditional process of drug discovery and development is time-consuming and expensive. Exploratory clinical trials, which are carried out in humans at an early stage of drug testing, provide pharmacological information that can be used to reduce attrition rates and minimize preclinical testing. The authors of this Review describe the concept of exploratory clinical trials and highlight new investigational drugs that could benefit patients with kidney disease.
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页码：469 / 477
页数：8
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