PReS-FINAL-2156: Analysis of gene expression and inflammation biomarkers in systemic juvenile idiopathic arthritis (SJIA) patients on canakinumab therapy

被引:0
|
作者
N Nirmala
N Wulffraat
H Brunner
P Quartier
R Brik
L Mccann
H Ozdogan
L Rutkowska-Sak
R Schneider
V Gerloni
L Harel
M Terreri
K Houghton
R Joos
D Kingsbury
J Lopez-Benitez
S Radominski
A Brachat
S Bek
M Schumacher
M Valentin
H Gram
K Abrams
A Martini
N Ruperto
D Lovell
机构
[1] NIBR,
[2] PRINTO-Istituto Gaslini,undefined
[3] PRCSG,undefined
[4] Necker-Enfant Malades Hospital,undefined
[5] Universidade Federal do Paraná,undefined
[6] NIBR,undefined
[7] Novartis Pharmaceuticals Corp,undefined
关键词
Macrophage Activation Syndrome; Canakinumab; Systemic Juvenile Idiopathic Arthritis; Blood Gene Expression; Total IL18;
D O I
10.1186/1546-0096-11-S2-P168
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Analysis of Biomarkers in Systemic Juvenile Idiopathic Arthritis Patients On Canakinumab Therapy.
    Wulffraat, Nico
    Brunner, Hermine I.
    Ruperto, Nicolino
    Quartier, Pierre
    Brik, Riva
    McCann, Liza
    Ozdogan, Huri
    Rutkowska-Sak, Lidia
    Schneider, Rayfel
    Gerloni, Valeria
    Harel, Liora
    Hilario, Maria
    Houghton, Kristin
    Joos, Rik
    Kingsbury, Daniel
    Brachat, Arndt
    Bek, Stephan
    Schumacher, Martin
    Valentin, Marie-Anne
    Nirmala, N. R.
    Gram, Hermann
    Abrams, Ken
    Martini, Alberto
    Lovell, D. J.
    [J]. ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : S328 - S328
  • [2] PReS-FINAL-2158: Effect of canakinumab on functional ability and health-related quality of life in systemic juvenile idiopathic arthritis (SJIA) patients
    P Quartier
    N Ruperto
    N Wulffraat
    H Brunner
    R Brik
    L Mccann
    H Foster
    M Frosch
    V Gerloni
    L Harel
    C Len
    K Houghton
    R Joos
    K Abrams
    K Lheritier
    S Kessabi
    A Martini
    D Lovell
    [J]. Pediatric Rheumatology, 11 (Suppl 2)
  • [3] CHANGES IN GENE EXPRESSION AND INFLAMMATORY PROTEINS IN SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS PATIENTS ON CANAKINUMAB THERAPY
    Brachat, A.
    Grom, A.
    Wulffraat, N.
    Brunner, H.
    Quartier, P.
    Brik, R.
    McCann, L.
    Ozdogan, H.
    Rutkowska-Sak, L.
    Schneider, R.
    Gerloni, V.
    Harel, L.
    Terreri, M.
    Houghton, K.
    Joos, R.
    Kingsbury, D.
    Lopez-Benitez, J.
    Bek, S.
    Schumacher, M.
    Valentin, M.
    Gram, H.
    Abrams, K.
    Martini, A.
    Ruperto, N.
    Lovell, D.
    Nirmala, N.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 62 - 62
  • [4] Characterization Of Changes In Gene Expression and Inflammatory Proteins In Systemic Juvenile Idiopathic Arthritis Patients On Canakinumab Therapy
    Nirmala, Nanguneri. R.
    Wulffraat, Nico
    Brunner, Hermine
    Quartier, Pierre
    Brik, Riva
    McCann, Liza
    Ozdogan, Huri
    Rutkowska-Sak, Lidia
    Schneider, Rayfel
    Gerloni, Valeria
    Harel, Liora
    Terreri, Maria
    Houghton, Kristin
    Joos, Rik
    Kingsbury, Daniel
    Lopez-Benitez, Jorge M.
    Brachat, Arndt
    Bek, Stephan
    Schumacher, Martin
    Valentin, Marie-Anne
    Gram, Hermann
    Abrams, Ken
    Martini, Alberto
    Ruperto, Nicolino
    Lovell, Daniel J.
    [J]. ARTHRITIS AND RHEUMATISM, 2013, 65 : S716 - S716
  • [5] Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy
    Brachat, Arndt H.
    Grom, Alexei A.
    Wulffraat, Nico
    Brunner, Hermine I.
    Quartier, Pierre
    Brik, Riva
    McCann, Liza
    Ozdogan, Huri
    Rutkowska-Sak, Lidia
    Schneider, Rayfel
    Gerloni, Valeria
    Harel, Liora
    Terreri, Maria
    Houghton, Kristin
    Joos, Rik
    Kingsbury, Daniel
    Lopez-Benitez, Jorge M.
    Bek, Stephan
    Schumacher, Martin
    Valentin, Marie-Anne
    Gram, Hermann
    Abrams, Ken
    Martini, Alberto
    Lovell, Daniel J.
    Nirmala, Nanguneri R.
    Ruperto, Nicolino
    [J]. ARTHRITIS RESEARCH & THERAPY, 2017, 19
  • [6] Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy
    Arndt H. Brachat
    Alexei A. Grom
    Nico Wulffraat
    Hermine I. Brunner
    Pierre Quartier
    Riva Brik
    Liza McCann
    Huri Ozdogan
    Lidia Rutkowska-Sak
    Rayfel Schneider
    Valeria Gerloni
    Liora Harel
    Maria Terreri
    Kristin Houghton
    Rik Joos
    Daniel Kingsbury
    Jorge M. Lopez-Benitez
    Stephan Bek
    Martin Schumacher
    Marie-Anne Valentin
    Hermann Gram
    Ken Abrams
    Alberto Martini
    Daniel J. Lovell
    Nanguneri R. Nirmala
    Nicolino Ruperto
    [J]. Arthritis Research & Therapy, 19
  • [7] Neutrophils Gene expression profile in systemic Juvenile Idiopathic Arthritis (sJIA) patients treated successfully with Anakinra
    Omoyinmi, Ebun
    Hamaoui, Raja
    Radziszewska, Anna
    Bryant, Annette
    Zheng, Dongling
    Banerjee, Priya
    Woo, Patricia
    [J]. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2011, 29 (02) : 437 - 437
  • [8] PReS-FINAL-2031: Hyaluronic acid is a marker of active arthritis, but not systemic inflammation in systemic juvenile idiopathic arthritis
    B Hugle
    M Olsson
    N Fischer
    M Herrmann
    K Lindblad-Toh
    JP Haas
    [J]. Pediatric Rheumatology, 11 (Suppl 2)
  • [9] PReS-FINAL-2140: Neutropenia with Tocilizumab (TCZ) treatment is not associated with increased infection risk in patients with systemic juvenile idiopathic arthritis (SJIA)
    F De Benedetti
    HI Brunner
    E Baildam
    R Burgos-Vargas
    G Horneff
    HI Huppertz
    K Minden
    BL Myones
    K Onel
    J Wang
    K Bharucha
    D Lovell
    A Martini
    N Ruperto
    [J]. Pediatric Rheumatology, 11 (Suppl 2)
  • [10] Efficacy of Canakinumab in Patients with Systemic Juvenile Idiopathic Arthritis (SJIA) using JADAS Criteria - an Analysis of 12-Week Pooled Data
    Ravelli, A.
    Brunner, H. I.
    Ruperto, N.
    Quartier, P.
    Consolaro, A.
    Wulffraat, N. M.
    Lheritier, K.
    Gaillez, C.
    Martini, A.
    Lovell, D. J.
    [J]. ARTHRITIS & RHEUMATOLOGY, 2014, 66 : S1002 - S1003