Oxidative stress in early diabetic nephropathy: fueling the fire

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作者
Dhruv K. Singh
Peter Winocour
Ken Farrington
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[1] Renal Unit,Department of Diabetes and Endocrinology
[2] Lister Hospital,undefined
[3] Queen Elizabeth II Hospital,undefined
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摘要
This Review summarizes the role of reactive oxygen species and oxidative stress in diabetes mellitus and in the pathogenesis of endothelial cell dysfunction and diabetic nephropathy. Furthermore, the authors explore possible therapeutic interventions to reduce oxidative stress and endothelial cell dysfunction and retard the progression of diabetic nephropathy.
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页码:176 / 184
页数:8
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