Induction and molecular signature of pathogenic TH17 cells

被引：0

作者：

Youjin Lee

Amit Awasthi

Nir Yosef

Francisco J Quintana

Sheng Xiao

Anneli Peters

Chuan Wu

Markus Kleinewietfeld

Sharon Kunder

David A Hafler

Raymond A Sobel

Aviv Regev

Vijay K Kuchroo

机构：

[1] Center for Neurologic Diseases,Department of Neurology

[2] Brigham and Women's Hospital,Palo Alto Veteran's Administration Health Care System and Department of Pathology

[3] Harvard Medical School,Department of Biology

[4] Broad Institute of MIT and Harvard,undefined

[5] Yale University School of Medicine,undefined

[6] Stanford University School of Medicine,undefined

[7] Howard Hughes Medical Institute,undefined

[8] Massachusetts Institute of Technology,undefined

[9] Present address: Translational Health Science & Technology Institute,undefined

[10] Faridabad,undefined

[11] Haryana,undefined

[12] India.,undefined

来源：

Nature Immunology | 2012年 / 13卷

关键词：

D O I：

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学科分类号：

摘要：

Exposure to interleukin 23 (IL-23) is required for the induction of pathogenic TH17 cells. Kuchroo and colleagues show that IL-23-dependent induction of the cytokine TGF-β3 produces a molecular signature characteristic of highly pathogenic TH17 cells.

引用

页码：991 / 999

页数：8

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