Effect of Endomorphin-1 on Contractile Activity of Rat Mesenteric Lymphatic Vessels

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作者
O. V. Nechaykina
S. G. Petunov
机构
[1] Federal Medical-Biological Agency of Russia,Research Institute of Hygiene, Occupational Pathology, and Human Ecology
关键词
isolated lymphatic vessels; endomorphin-1; opioid receptors;
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摘要
We studied the effect of endomorphin-1 on isolated mesenteric lymphatic vessels in rats. It was found that endomorphin-1 caused a dose-dependent increase in the contractile activity of lymphangions, which was associated with stimulation of intracellular calcium depots. The observed effect of endomorphin-1 in isolated lymphatic vessels has a complex mechanism; it depends on the concentration of the applied peptide and is probably determined by its interaction with non-opioid receptors
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页码:55 / 57
页数:2
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