A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity

被引:0
|
作者
C Peter Bengtson
Oliver Dick
Hilmar Bading
机构
[1] University of Heidelberg,Department of Neurobiology, Interdisciplinary Centre for Neurosciences (IZN)
来源
关键词
NMDA Receptor; cAMP Response Element Binding; Hippocampal Culture; Current Clamp Mode; Synaptic Receptor;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 31 条
  • [1] A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity
    Bengtson, C. Peter
    Dick, Oliver
    Bading, Hilmar
    BMC NEUROSCIENCE, 2008, 9 (1)
  • [2] Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
    Shu-ichi Okamoto
    Mahmoud A Pouladi
    Maria Talantova
    Dongdong Yao
    Peng Xia
    Dagmar E Ehrnhoefer
    Rameez Zaidi
    Arjay Clemente
    Marcus Kaul
    Rona K Graham
    Dongxian Zhang
    H-S Vincent Chen
    Gary Tong
    Michael R Hayden
    Stuart A Lipton
    Nature Medicine, 2009, 15 : 1407 - 1413
  • [3] Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
    Okamoto, Shu-ichi
    Pouladi, Mahmoud A.
    Talantova, Maria
    Yao, Dongdong
    Xia, Peng
    Ehrnhoefer, Dagmar E.
    Zaidi, Rameez
    Clemente, Arjay
    Kaul, Marcus
    Graham, Rona K.
    Zhang, Dongxian
    Chen, H-S Vincent
    Tong, Gary
    Hayden, Michael R.
    Lipton, Stuart A.
    NATURE MEDICINE, 2009, 15 (12) : 1407 - U8
  • [4] Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function
    Gladding, Clare M.
    Raymond, Lynn A.
    MOLECULAR AND CELLULAR NEUROSCIENCE, 2011, 48 (04) : 308 - 320
  • [5] Protective action of fingolimod against acute Aβ neurotoxicity by rapid synaptic relocation of NMDA receptor in hippocampal neurons
    Joshi, P.
    Gabrielli, M.
    Ponzoni, L.
    Pelucchi, S.
    Stravalaci, M.
    Beeg, M.
    Mazzitelli, S.
    Braida, B.
    Sala, M.
    Boda, E.
    Buffo, A.
    Gobbi, M.
    Gardoni, F.
    Matteoli, M.
    Marcello, E.
    Verderio, C.
    JOURNAL OF ALZHEIMERS DISEASE, 2016, 53 : S33 - S34
  • [6] Fingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal Neurons
    Joshi, Pooja
    Gabrielli, Martina
    Ponzoni, Luisa
    Pelucchi, Silvia
    Stravalaci, Matteo
    Beeg, Marten
    Mazzitelli, Sonia
    Braida, Daniela
    Sala, Mariaelvina
    Boda, Enrica
    Buffo, Annalisa
    Gobbi, Marco
    Gardoni, Fabrizio
    Matteoli, Michela
    Marcello, Elena
    Verderio, Claudia
    SCIENTIFIC REPORTS, 2017, 7
  • [7] Fingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal Neurons
    Pooja Joshi
    Martina Gabrielli
    Luisa Ponzoni
    Silvia Pelucchi
    Matteo Stravalaci
    Marten Beeg
    Sonia Mazzitelli
    Daniela Braida
    Mariaelvina Sala
    Enrica Boda
    Annalisa Buffo
    Marco Gobbi
    Fabrizio Gardoni
    Michela Matteoli
    Elena Marcello
    Claudia Verderio
    Scientific Reports, 7
  • [8] Modulating the Balance of Synaptic and Extrasynaptic NMDA Receptors Shows Positive Effects against Amyloid-β-Induced Neurotoxicity
    Huang, Yan
    Shen, Wei
    Su, Jie
    Cheng, Bin
    Li, Dong
    Liu, Gang
    Zhou, Wen-Xia
    Zhang, Yong-Xiang
    JOURNAL OF ALZHEIMERS DISEASE, 2017, 57 (03) : 885 - 897
  • [9] Imbalance between synaptic and extrasynaptic NMDA receptor function in an animal model of chronic social defeat stress
    Wong, T. -P.
    Tse, Y. C.
    JOURNAL OF NEUROCHEMISTRY, 2014, 130 : 19 - 19
  • [10] Protective effect of a novel AMPA and NMDA antagonist kaitocephalin against glutamate neurotoxicity
    Shin-ya, K
    Kim, JS
    Hayakawa, Y
    Seto, H
    JOURNAL OF NEUROCHEMISTRY, 1999, 73 : S190 - S190