The Behavior of Dimethylamino-substituted 2,5-Diaryloxazoles and 2,5-Diaryl-1,3,4-oxadiazoles Under Vilsmeier-Haack Conditions

被引：0
|
作者：
L. D. Patsenker
I. G. Ermolenko
O. N. Lyubenko
I. A. Fedyunyaeva
N. A. Popova
O. S. Galkina
A. V. Mazepa
B. M. Krasovitskii
机构：
[1] Institute of Monocrystals,Ukraine National Academy of Sciences
[2] A. V. Bogatsky Physico-Chemical Institute,Ukraine National Academy of Sciences
来源：
Chemistry of Heterocyclic Compounds | 2003年 / 39卷 / 4期
关键词：
2,5-diaryloxazoles; 2,5-diaryl-1,3,4-oxadiazoles; dimethylamino-substituted; quinazolinium salts; heterocyclization; hydrolysis; Vilsmeier reaction;
D O I：
10.1023/A:1024777700217
中图分类号：
学科分类号：
摘要：
It has been shown that dimethylamino-substituted 2,5-diaryloxazoles and 2,5-diaryl-1,3,4-oxadiazoles undergo heterocyclization under Vilsmeier-Haack conditions with the participation of the dimethylamino group to form quinazolinium salts. The oxazole ring can also be formylated at the free 4 position. In alkaline medium the quinazolinium ring is readily hydrolyzed with desalkylation.
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页码：525 / 533
页数：8
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