Skin Penetration and Mechanisms of Action in the Delivery of the D2-Agonist Rotigotine from Surfactant-Based Elastic Vesicle Formulations

被引:0
|
作者
P. Loan Honeywell-Nguyen
Sonia Arenja
Joke A. Bouwstra
机构
[1] University of Leiden,Department of Pharmaceutical Technology, Leiden/Amsterdam Center for Drug Research
来源
Pharmaceutical Research | 2003年 / 20卷
关键词
transdermal delivery; elastic vesicles; rotigotine; drug carrier systems;
D O I
暂无
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学科分类号
摘要
Purpose. This study was performed to investigate the effect of elastic and rigid vesicles on the penetration of the D2 dopamine agonist rotigotine across human skin and to further elucidate the mechanisms of action of the elastic vesicles.
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页码:1619 / 1625
页数:6
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