Cytomegalovirus infection in pediatric rheumatic diseases: a review

被引：0
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作者：
Eli M Eisenstein
Dana G Wolf
机构：
[1] Hadassah-Hebrew University Medical Center,Department of Pediatrics
[2] Hadassah-Hebrew University Medical Center,Department of Clinical Microbiology & Infectious Diseases
来源：
Pediatric Rheumatology | / 8卷
关键词：
Systemic Lupus Erythematosis; Systemic Lupus Erythematosis Patient; Macrophage Activation Syndrome; Mixed Connective Tissue Disease; HCMV Infection;
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摘要：
Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this article we discuss the interplay between HCMV and the immune system, and review the clinical manifestations, diagnosis, and treatment of HCMV infection in children with rheumatic disease.
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