A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning

被引：1
|
作者：
Sutherland K. [1 ,2 ]
Miyajima S. [2 ]
Date H. [1 ]
Shirato H. [1 ]
Ishikawa M. [1 ]
Murakami M. [4 ]
Yamagiwa M. [3 ]
Bolton P. [3 ]
Tajima T. [3 ]
机构：
[1] Hokkaido University School of Medicine, Sapporo 060-0812
[2] Japan Science and Technology, Kawaguchi, Saitama 332-0012
[3] Photo-Medical Research Center, Japan Atomic Energy Agency, Kizugawa
[4] Hyogo Ion Beam Medical Center, Tatsuno, Hyogo
来源：
Radiological Physics and Technology | 2010年 / 3卷 / 1期
基金：
日本科学技术振兴机构;
关键词：
Laser acceleration; Monte Carlo simulation; Ocular melanoma; Proton therapy;
D O I：
10.1007/s12194-009-0071-4
中图分类号：
学科分类号：
摘要：
The results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot scanning method utilizing active energy modulation, which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread was suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and the required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators. © 2009 Japanese Society of Radiological Technology and Japan Society of Medical Physics.
引用
收藏
页码：16 / 22
页数：6
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