A Study of Promethazine Hydrochloride and Pentazocine Intramuscular Sedation Along with 2 % Lidocaine Hydrochloride and Adrenaline and Comparison to Placebo Along with 2 % Lidocaine Hydrochloride and Adrenaline for Surgical Extraction of Mandibular Third Molar

Background and Objectives: The main objective is to study and compare the sedative and analgesic effects of intramuscular injection fortwin–phenergan along with local anesthetic and normal saline placebo along with local anesthetics in mandibular third molar surgery. We also assessed and compared the postoperative experience of the patient in relation to the pain intensity, time to first analgesic taken and total number of analgesics consumed over a period of 48 h in the two groups. Materials and Methods: Patients who came to the Department of Oral and Maxillofacial Surgery, The Regional Dental College; with complaints regarding mandibular third molar were chosen for the treatment. Patients were evaluated using Corah Dental Anxiety Scale (CDAS) and those patients having a score of CDAS 13 and above were selected. Sixty patients were selected out of which 30 patients formed group 1 and another 30 patients group 2. The patients were randomly divided with flip method into group 1 (study group) and or group 2 (controlled group). Results: Our study results showed that the operating conditions for both the groups at the end of surgery were similar without significant difference. Most of the surgical procedures were graded as excellent and good in both the groups except that difficulty was encountered in two patients from group 1 and one from group 2. Conclusion: It could be concluded that particular drugs do not have much influence on the surgical procedure in our study, but it was found that patients from group 1 were more cooperative as compared to group 2 when difficulty was encountered during the surgical procedure. © 2013, Association of Oral and Maxillofacial Surgeons of India.