The changing approach for identifying hereditary colorectal cancer syndromes

被引：0
|
作者：
Luigi Laghi
Luigi Ricciardiello
机构：
[1] University of Parma,Department of Medicine and Surgery
[2] Humanitas Clinical and Research Centre — IRCCS —,Laboratory of Molecular Gastroenterology
[3] University of Bologna,Department of Medical and Surgical Sciences
[4] University of Bologna,Center for the Studies of Hereditary Cancers, Department of Medical and Surgical Sciences
[5] University of Bologna,Center for Applied Biomedical Research
[6] Sant’Orsola-Malpighi Hospital,undefined
来源：
Nature Reviews Gastroenterology & Hepatology | 2020年 / 17卷
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摘要：
Data based on next-generation sequencing (NGS) of colorectal cancers (CRC) clearly show that up to 10% of all cases harbour pathogenic variants. Thus, NGS performed for all patients with CRC under the age of 50 could be a cost-effective strategy, leading to a personalized approach to patients and family members.
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页码：593 / 594
页数：1
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