EANM enabling guide: how to improve the accessibility of clinical dosimetry

被引:0
|
作者
Jonathan Gear
Caroline Stokke
Christelle Terwinghe
Silvano Gnesin
Mattias Sandström
Johannes Tran-Gia
Marta Cremonesi
Francesco Cicone
Fredrik Verburg
Roland Hustinx
Luca Giovanella
Ken Herrmann
Pablo Minguez Gabiña
机构
[1] Royal Marsden NHSFT & Institute of Cancer Research,Joint Department of Physics
[2] Oslo University Hospital,Division of Radiology and Nuclear Medicine
[3] University of Oslo,Department of Physics
[4] Universitair Ziekenhuis Leuven,Department of Nuclear Medicine
[5] University of Lausanne,Institute of Radiation Physics, Lausanne University Hospital
[6] Uppsala University,Section of Nuclear Medicine and PET, Department of Surgical Sciences
[7] Uppsala University,Sweden & Section of Medical Physics, Department of Immunology, Genetics and Pathology
[8] University Hospital Würzburg,Department of Nuclear Medicine
[9] Istituto Europeo Di Oncologia,Radiation Research Unit, Department of Medical Imaging and Radiation Sciences
[10] IRCCS,Department of Experimental and Clinical Medicine, Neuroscience Research Centre, PET/RM Unit
[11] “Magna Graecia” University of Catanzaro,Nuclear Medicine Unit
[12] University Hospital “Mater Domini,Department of Radiology and Nuclear Medicine
[13] Erasmus Medical Center,Division of Nuclear Medicine and Oncological Imaging
[14] University Hospital of Liège,GIGA
[15] University of Liège,CRC in Vivo Imaging
[16] Imaging Institute of Southern Switzerland,Clinic for Nuclear Medicine and Molecular Imaging
[17] Ente Ospedaliero Cantonale,Department of Nuclear Medicine
[18] University of Duisburg-Essen,Department of Medical Physics and Radiation Protection
[19] German Cancer Consortium (DKTK)-University Hospital Essen,Department of Applied Physics, Faculty of Engineering
[20] Gurutzeta-Cruces University Hospital/Biocruces Health Research Institute,undefined
[21] UPV/EHU,undefined
关键词
Dosimetry; Molecular radiotherapy; SPECT; Nuclear medicine; Quantitative imaging; Optimisation;
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摘要
Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry and demonstrates how a dosimetry regimen can be tailored to the available facilities of a centre. The aim is to help centres wishing to initiate a dosimetry service but may not have the experience or resources of some of the more established therapy and dosimetry centres. The multidisciplinary approach and different personnel requirements are discussed and key equipment reviewed example protocols demonstrating these factors are given in the supplementary material for the main therapies carried out in nuclear medicine, including [131I]-NaI for benign thyroid disorders, [177Lu]-DOTATATE and 131I-mIBG for neuroendocrine tumours and [90Y]-microspheres for unresectable hepatic carcinoma.
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页码:1861 / 1868
页数:7
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