Principles and effects of microRNA-mediated post-transcriptional gene regulation

被引:0
|
作者
B M Engels
G Hutvagner
机构
[1] College of Life Sciences,Division of Gene regulation and Expression
[2] University of Dundee,undefined
来源
Oncogene | 2006年 / 25卷
关键词
miRNA; RISC formation; translational repression; P-body;
D O I
暂无
中图分类号
学科分类号
摘要
MicroRNAs (miRNAs) are abundant regulatory RNAs involved in the regulation of many key biological processes. Recent advances in understanding the mechanism of RNA interference and miRNA-mediated mechanisms shed light on major principals of the formation of the regulatory complex and provide models to explain how these small regulatory RNA species interfere with gene expression and how they influence the translational status of the transcriptome.
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收藏
页码:6163 / 6169
页数:6
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