Solubility and phase transitions in the water-protein-salt system

The analytical expressions previously obtained for the lines characterizing various phase transitions (sol-gel, liquid-liquid, liquid-solid) that relate the critical molar composition of the water-protein-salt system to individual features of its components (protein charge z, number v of adsorbed ions, and electrolyte activity function Δ) are represented in conventional coordinates of logarithm of protein solubility logS versus salt concentration m 3. The tendencies of the changes in the positions of phase transition lines in these coordinates as dependent on the parameters v and z and their ratio are determined. The relationship of the salting-out line and the salting-out coefficient with phase transitions is discussed. © Nauka/Interperiodica 2006.