Miltefosine (Impavido): the first oral treatment against leishmaniasis

被引：0

作者：

H. Sindermann

S. L. Croft

K. R. Engel

W. Bommer

H. J. Eibl

C. Unger

J. Engel

机构：

[1] Zentaris AG,Georg

[2] London School of Hygiene and Tropical Medicine,August

[3] Institute of Hygiene,University of Göttingen

[4] Max-Planck-Institut für Biophysikalische Chemie,undefined

[5] Klinik für Tumorbiologie,undefined

来源：

Medical Microbiology and Immunology | 2004年 / 193卷

关键词：

Visceral leishmaniasis; Miltefosine; Oral activity; Antimonial resistance;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Miltefosine is a novel antileishmanial drug that has significant selectivity in both in vitro and in vivo models. Clinical efficacy was demonstrated for the treatment of visceral leishmaniasis with the advantage of oral administration over the currently recommended antileishmanial drugs that require parenteral administration. Miltefosine produces high cure rates also in patients resistant to the standard antimonial therapy.

引用

页码：173 / 180

页数：7

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