Target class drug discovery

被引：0
|
作者：
Kimberly D Barnash
Lindsey I James
Stephen V Frye
机构：
[1] Center for Integrative Chemical Biology and Drug Discovery,Division of Chemical Biology and Medicinal Chemistry
[2] UNC Eshelman School of Pharmacy,undefined
[3] University of North Carolina at Chapel Hill,undefined
来源：
Nature Chemical Biology | 2017年 / 13卷
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学科分类号：
摘要：
Selection of molecular targets based on disease understanding is a dominant paradigm in drug discovery. We argue that a focus on classes of targets with central roles in biology provides a complementary approach that has higher quality outcomes in early discovery efforts.
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页码：1053 / 1056
页数：3
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