Cannabidiol-induced panicolytic-like effects and fear-induced antinociception impairment: the role of the CB1 receptor in the ventromedial hypothalamus

被引:0
|
作者
Asmat Ullah Khan
Luiz Luciano Falconi-Sobrinho
Tayllon dos Anjos-Garcia
Maria de Fátima dos Santos Sampaio
José Alexandre de Souza Crippa
Leda Menescal-de-Oliveira
Norberto Cysne Coimbra
机构
[1] Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP),Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology
[2] The University of Poonch Rawalakot,Department of Eastern Medicine and Surgery, School of Medical and Health Sciences
[3] Hajira Road,Neurobiology of Emotions (NAP
[4] Ribeirão Preto School of Medicine of the University of São Paulo (FMRP-USP),USP
[5] Behavioural Neurosciences Institute (INeC),NuPNE) Research Centre
[6] Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP),Department of Neuroscience and Behavioural Sciences, Division of Psychiatry
[7] Ribeirão Preto Medical School of the University of São Paulo,Laboratory of Neurophysiology, Department of Physiology
来源
Psychopharmacology | 2020年 / 237卷
关键词
Cannabidiol; CB; receptor; Panic attack-like behaviour; Endocannabinoid system; Unconditioned fear-induced antinociception; Ventromedial hypothalamus;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1063 / 1079
页数:16
相关论文
共 50 条
  • [1] Cannabidiol-induced panicolytic-like effects and fear-induced antinociception impairment: the role of the CB1 receptor in the ventromedial hypothalamus
    Khan, Asmat Ullah
    Falconi-Sobrinho, Luiz Luciano
    dos Anjos-Garcia, Tayllon
    Sampaio, Maria de Fatima dos Santos
    Crippa, Jose Alexandre de Souza
    Menescal-de-Oliveira, Leda
    Coimbra, Norberto Cysne
    [J]. PSYCHOPHARMACOLOGY, 2020, 237 (04) : 1063 - 1079
  • [2] CB1 receptor signalling mediates cannabidiol-induced panicolytic-like effects and defensive antinociception impairment in mice threatened by Bothrops jararaca lancehead pit vipers
    de Paula Rodrigues, Bruno Mangili
    Coimbra, Norberto Cysne
    [J]. JOURNAL OF PSYCHOPHARMACOLOGY, 2022, 36 (12) : 1384 - 1396
  • [3] Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor
    de Freitas, Renato Leonardo
    Salgado-Rohner, Carlos Jose
    Cecilio Hallak, Jaime Eduardo
    de Souza Crippa, Jose Alexandre
    Coimbra, Norberto Cysne
    [J]. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2013, 16 (08): : 1781 - 1798
  • [4] GABAA receptor blockade in dorsomedial and ventromedial nuclei of the hypothalamus evokes panic-like elaborated defensive behaviour followed by innate fear-induced antinociception
    Freitas, Renato Leonardo
    Uribe-Marino, Andres
    Castiblanco-Urbina, Maria Angelica
    Elias-Filho, Daoud Hibraim
    Coimbra, Norberto Cysne
    [J]. BRAIN RESEARCH, 2009, 1305 : 118 - 131
  • [5] Dissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata, and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior colliculus: The role of CB1-cannabinoid receptor in the ventral mesencephalon
    da Silva, Juliana Almeida
    Biagioni, Audrey Francisco
    Almada, Rafael Carvalho
    de Souza Crippa, Jose Alexandre
    Cecilio Hallak, Jaime Eduardo
    Zuardi, Antonio Waldo
    Coimbra, Norberto Cysne
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 758 : 153 - 163
  • [6] A time-dependent contribution of hippocampal CB1, CB2 and PPARγ receptors to cannabidiol-induced disruption of fear memory consolidation
    Raymundi, Ana Maria
    da Silva, Thiago R.
    Zampronio, Aleksander R.
    Guimaraes, Francisco S.
    Bertoglio, Leandro J.
    Stern, Cristina A. J.
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 2020, 177 (04) : 945 - 957
  • [7] Central antinociception induced by μ-opioid receptor agonist morphine, but not δ- or κ-, is mediated by cannabinoid CB1 receptor
    Pacheco, Daniela da Fonseca
    Klein, Andre
    Perez, Andrea Castro
    da Fonseca Pacheco, Cinthia Mara
    de Francischi, Janetti Nogueira
    Lopes Reis, Glaucia Maria
    Gama Duarte, Igor Dimitri
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 2009, 158 (01) : 225 - 231
  • [8] Role of the cannabinoid CB1 receptor in methamphetamine-induced social and recognition memory impairment
    Khodamoradi, Mehdi
    Tirgar, Fatemeh
    Ghazvini, Hamed
    Rafaiee, Raheleh
    Tamijani, Seyedeh Masoumeh Seyedhosseini
    Karimi, Narges
    Yadegari, Ali
    Khachaki, Ali Siahposht
    Akhtari, Javad
    [J]. NEUROSCIENCE LETTERS, 2022, 779
  • [9] The Nitric Oxide Donor SIN-1-Produced Panic-Like Behaviour And Fear-Induced Antinociception Are Modulated By NMDA Receptors In The Anterior Hypothalamus
    Falconi-Sobrinho, Luiz Luciano
    Coimbra, Norberto Cysne
    [J]. JOURNAL OF PSYCHOPHARMACOLOGY, 2018, 32 (06) : 711 - 722
  • [10] Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Hippocampus: Cannabidiol Blunts Δ9-Tetrahydrocannabinol-Induced Cognitive Impairment
    Ester Aso
    Víctor Fernández-Dueñas
    Marc López-Cano
    Jaume Taura
    Masahiko Watanabe
    Isidre Ferrer
    Rafael Luján
    Francisco Ciruela
    [J]. Molecular Neurobiology, 2019, 56 : 5382 - 5391