Proinflammatory cytokine production and insulin sensitivity regulated by overexpression of resistin in 3T3-L1 adipocytes

被引：0
|
作者：
Yuchang Fu
Liehong Luo
Nanlan Luo
W Timothy Garvey
机构：
[1] University of Alabama at Birmingham,Department of Nutrition Sciences
[2] Birmingham Veterans Affairs Medical Center,undefined
来源：
Nutrition & Metabolism | / 3卷
关键词：
Adipocyte Differentiation; Glucose Transport System; GLUT4 Gene Expression; GLUT4 mRNA Level; Resistin Protein;
D O I：
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学科分类号：
摘要：
Resistin is secreted from adipocytes, and high circulating levels have been associated with obesity and insulin resistance. To investigate whether resistin could exert autocrine effects in adipocytes, we expressed resistin gene in 3T3-L1 fibroblasts using a lentiviral vector, and selected several stably-transduced cell lines under blasticidin selection.
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