UCN-01 induces S and G2/M cell cycle arrest through the p53/p21waf1or CHK2/CDC25C pathways and can suppress invasion in human hepatoma cell lines

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作者
Guoyi Wu
Linan Xu
Nan Lin
Bo Liu
机构
[1] Sun Yat-Sen University,Department of General Surgery, the Lingnan Hospital, the Third Affiliated Hospital
[2] Sun Yat-Sen University,Department of Gynecology and Obstetrics, the First Affiliated Hospital
[3] Sun Yat-Sen University,Department of Hepatobiliary Surgery, the Third Affiliated Hospital
来源
BMC Cancer | / 13卷
关键词
7-hydroxystaurosporine (UCN-01); G2/M arrest; S arrest; Hepatocellular carcinoma; Anti-cancer drug; Beta-catenin; Tumour invasion and migration;
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