Effects of an endothelin receptor antagonist, Macitentan, on right ventricular substrate utilization and function in a Sugen 5416/hypoxia rat model of severe pulmonary arterial hypertension

被引：0
|
作者：
Katarzyna Drozd
Ali Ahmadi
Yupu Deng
Baohua Jiang
Julia Petryk
Stephanie Thorn
Duncan Stewart
Rob Beanlands
Robert A. deKemp
Jean N. DaSilva
Lisa M. Mielniczuk
机构：
[1] University of Ottawa Heart Institute,Division of Cardiology, Department of Medicine
[2] Ottawa Hospital Research Institute,Department of Cardiac Imaging
[3] University of Ottawa Heart Institute,Department of Radiology, Radio
[4] University of Montreal,Oncology and Nuclear Medicine
[5] University of Montreal Hospital Research Centre (CRCHUM),undefined
来源：
Journal of Nuclear Cardiology | 2017年 / 24卷
关键词：
Fatty acid imaging; heart failure; fluorodeoxyglucose (FDG); microPET imaging; metabolism; PET;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1979 / 1989
页数：10
相关论文
共 50 条
  • [1] Effects of an endothelin receptor antagonist, Macitentan, on right ventricular substrate utilization and function in a Sugen 5416/hypoxia rat model of severe pulmonary arterial hypertension
    Drozd, Katarzyna
    Ahmadi, Ali
    Deng, Yupu
    Jiang, Baohua
    Petryk, Julia
    Thorn, Stephanie
    Stewart, Duncan
    Beanlands, Rob
    deKemp, Robert A.
    DaSilva, Jean N.
    Mielniczuk, Lisa M.
    [J]. JOURNAL OF NUCLEAR CARDIOLOGY, 2017, 24 (06) : 1979 - 1989
  • [2] The novel endothelin receptor antagonist, Macitentan, improves right ventricular energetics and function in the Sugen5416/hypoxia rat model of severe pulmonary artery hypertension
    Drozd, K.
    Deng, Y.
    Jiang, B.
    Lockwood, J.
    Thorn, S.
    Stewart, D.
    Beanlands, R. S.
    Dekemp, R. S.
    Dasilva, J.
    Mielniczuk, L. M.
    [J]. EUROPEAN HEART JOURNAL, 2014, 35 : 761 - 761
  • [3] The Novel Endothelin Receptor Antagonist, Macitentan, Improved Right Ventricular Function and Normalized Glucose Uptake in a Sugen5416/hypoxia Rat Model of Severe Pulmonary Artery Hypertension
    Drozd, Katarzyna
    Deng, Yupu
    Jiang, Baohua
    Lockwood, Julia
    Thorn, Stephanie
    Stewart, Duncan J.
    Beanlands, Rob
    deKemp, Rob
    DaSilva, Jean
    Mielniczuk, Lisa M.
    [J]. JOURNAL OF CARDIAC FAILURE, 2014, 20 (08) : S73 - S74
  • [4] Echocardiographyc and histomorphometric assessment of the effects of pharmacological antagonism of endothelin receptors in the Sugen 5416/hypoxia rat model of pulmonary hypertension
    Cantoni, Silvia
    Cavalli, Stefano
    Pastore, Fiorella
    Nassini, Romina
    De Logu, Francesco
    Villetti, Gino
    Facchinetti, Fabrizio
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2018, 52
  • [5] ELEVATED FATTY ACID AND GLUCOSE UPTAKE IN RIGHT VENTRICLE IN A SUGEN 5416/HYPOXIA RAT MODEL OF SEVERE PULMONARY ARTERY HYPERTENSION
    Drozd, K.
    Deng, Y.
    Jiang, B.
    Lockwood, J.
    Thorn, S. L.
    Klein, R.
    Stewart, D. J.
    Beanlands, R. S.
    deKemp, R. A.
    DaSilva, J. N.
    Mielniczuk, L. M.
    [J]. CANADIAN JOURNAL OF CARDIOLOGY, 2013, 29 (10) : S249 - S249
  • [6] Novel Dual Endothelin Receptor Antagonist Macitentan Reverses Severe Pulmonary Arterial Hypertension in Rats
    Kunita-Takanezawa, Mutsumi
    Abe, Kohtaro
    Hirooka, Yoshitaka
    Kuwabara, Yukimitsu
    Hirano, Katsuya
    Oka, Masahiko
    Sunagawa, Kenji
    [J]. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2014, 64 (05) : 473 - 480
  • [7] Treatment of pulmonary arterial hypertension with macitentan, dual endothelin receptor antagonist
    Bichara, Valentina M.
    Bevacqua, Raul J.
    [J]. INSUFICIENCIA CARDIACA, 2019, 14 (03) : 119 - 128
  • [8] Right ventricular remodelling and inflammation in monocrotaline-induced pulmonary hypertension: effects of the endothelin receptor antagonist macitentan
    Rohm, I.
    Gruen, K.
    Foerster, M.
    Fritzenwanger, M.
    Bauer, R.
    Yilmaz, A.
    Pistulli, R.
    Jung, C.
    Berndt, A.
    Schulze, P. C.
    Franz, M.
    [J]. EUROPEAN HEART JOURNAL, 2018, 39 : 804 - 804
  • [9] The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan
    Williams, Thomas L.
    Nyimanu, Duuamene
    Kuc, Rhoda E.
    Foster, Richard
    Glen, Robert C.
    Maguire, Janet J.
    Davenport, Anthony P.
    [J]. FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [10] Differential Effects of Three Distinct Exercise Training Approaches on Right Ventricular Function and Mortality in a Sugen-Hypoxia Rat Model of Severe Pulmonary Arterial Hypertension (PAH)
    Brown, M.
    Frump, A. L.
    Long, G. M.
    Troutman, A.
    Fisher, A.
    Presson, R. G.
    Lahm, T.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 197
12345