X-ray computed tomography in life sciences

被引:0
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作者
Shelley D. Rawson
Jekaterina Maksimcuka
Philip J. Withers
Sarah H. Cartmell
机构
[1] The University of Manchester,The Henry Royce Institute and School of Materials
来源
BMC Biology | / 18卷
关键词
X-ray computed tomography; Correlative microscopy; Phase contrast; Lightsheet; Time-lapse tomography; 3D imaging; 3D histology; Elemental mapping; Quantitative tomography; Water window;
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摘要
Recent developments within micro-computed tomography (μCT) imaging have combined to extend our capacity to image tissue in three (3D) and four (4D) dimensions at micron and sub-micron spatial resolutions, opening the way for virtual histology, live cell imaging, subcellular imaging and correlative microscopy. Pivotal to this has been the development of methods to extend the contrast achievable for soft tissue. Herein, we review the new capabilities within the field of life sciences imaging, and consider how future developments in this field could further benefit the life sciences community.
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