Reflections on the immunology of tuberculosis: will we ever unravel the skein?

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作者
Maurizio de Martino
Luisa Galli
Elena Chiappini
机构
[1] Meyer Children University Hospital,Department of Health Sciences
[2] University of Florence,undefined
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Tuberculosis; Mycobacterium Tuberculosis; Active Tuberculosis; Mycobacterial Infection; Early Inflammatory Response;
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摘要
Many and large dumps exist in our knowledge about Mycobacterium tuberculosis infection and disease in infants and children. We still do not understand why some individuals do acquire and others do not acquire the infection in the presence of the same risk factors. We do not understand why some individuals convert from latent to active tuberculosis and why other individuals convert from active to inactive tuberculosis even without treatment.
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