Histopathological diagnosis and prognostic factors in adrenocortical carcinoma

被引:0
|
作者
Motohiko Aiba
Mariko Fujibayashi
机构
[1] Tokyo Women’s Medical University Daini Hospital,Department of Surgical Pathology
来源
Endocrine Pathology | 2005年 / 16卷
关键词
Adrenocortical carcinoma; histopathological diagnosis; Weiss’ criteria; prognostic factors; clear cell/compact cell morphology; functioning tumor; pediatric tumor; cytochrome P450aldo; P45011β; Insulin-like growth factor II (IGF-II);
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学科分类号
摘要
A great majority of adrenocortical tumors are benign, and many adrenocortical carcinomas (ACC) are obviously malignant at presentation. The histopathological diagnosis of ACC is occasionally difficult, particularly with stage I and stage II disease. The prognosis of ACC is generally poor. Surgery is the major treatment, with chemotherapy and radio-therapy being applicable to only restricted patients. The Weiss criteria are useful in diagnosing the common adult type of ACC. Histopathological prognostic factors of ACC have not been fully established because of the rarity of the disease.
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页码:13 / 22
页数:9
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