Determination of maltodextrins in enteral formulations by three different chromatographic methods

被引:0
|
作者
F. J. Moreno
A. Olano
G. Santa-María
N. Corzo
机构
[1] Instituto de Fermentaciones Industriales (C.S.I.C.),
来源
Chromatographia | 1999年 / 50卷
关键词
Thin-layer chromatography; Column liquid chromatography; Ion exchange; Maltodextrins; Enteral formulations;
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摘要
Maltodextrins (G1 to G11) present in enteral formulations have been determined by three analytical methods —thin-layer chromatography (TLC), high-performance anion-exchange chromatography with pulsed electrochemical detection (HPAEC-PED), and high-performance liquid chromatography with refractive-index detection (HPLC-RI). The repeatability of the three methods was similar. Although HPAEC-PED was more sensitive than HPLC-RI and TLC, the relatively high maltodextrin content of the enteral formulations resulted in reasonable agreement among results from quantitative determination of G1 to G7 by the three methods studied. Differences between methods were higher for compounds G8 to G11.
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页码:705 / 710
页数:5
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