Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

被引：0
|
作者：
Derk ten Berge
Dorota Kurek
Tim Blauwkamp
Wouter Koole
Alex Maas
Elif Eroglu
Ronald K. Siu
Roel Nusse
机构：
[1] Erasmus MC Stem Cell Institute,Department of Cell Biology
[2] Erasmus Medical Center,and Department of Developmental Biology
[3] Howard Hughes Medical Institute,Department of Cell Biology
[4] Stanford University School of Medicine,undefined
[5] Erasmus Medical Center,undefined
来源：
Nature Cell Biology | 2011年 / 13卷
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摘要：
ten Berge and colleagues show that Wnt signalling is required for self-renewal of embryonic stem cells through inhibition of their differentiation into epiblast stem cells. Together, Wnt and LIF signalling can support derivation and self-renewal of embryonic stem cells.
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页码：1070 / 1075
页数：5
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