A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma

被引：0

作者：

Jianping Yuan

Satoshi Kashiwagi

Patrick Reeves

Jean Nezivar

Yuan Yang

Nadiah Hashim Arrifin

Mai Nguyen

Gilberte Jean-Mary

Xiaoyun Tong

Paramjit Uppal

Svetlana Korochkina

Ben Forbes

Tao Chen

Elda Righi

Roderick Bronson

Huabiao Chen

Sandra Orsulic

Timothy Brauns

Pierre Leblanc

Nathalie Scholler

Glenn Dranoff

Jeffrey Gelfand

Mark C Poznansky

机构：

[1] Massachusetts General Hospital,Vaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine

[2] Harvard Medical School,Department of Pathology

[3] MIT and Harvard University,Ragon Institute of MGH

[4] Cedars-Sinai Medical Center,Women’s Cancer Research Institute

[5] University of Pennsylvania,Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology

[6] Dana-Farber Cancer Institute,Department of Medical Oncology and Cancer Vaccine Center

[7] Harvard Medical School,Department of Medicine, Brigham and Women’s Hospital

来源：

Journal of Hematology & Oncology | / 7卷

关键词：

Mycobacterial Hsp70; Mesothelin; Single chain variable fragment; Cancer immunotherapy; Murine tumor model;

D O I：

暂无

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学科分类号：

摘要：

引用

共 4 条

[1] A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma
Yuan, Jianping
Kashiwagi, Satoshi
Reeves, Patrick
Nezivar, Jean
Yang, Yuan
Arrifin, Nadiah Hashim
Nguyen, Mai
Jean-Mary, Gilberte
Tong, Xiaoyun
Uppal, Paramjit
Korochkina, Svetlana
Forbes, Ben
Chen, Tao
Righi, Elda
Bronson, Roderick
Chen, Huabiao
Orsulic, Sandra
Brauns, Timothy
Leblanc, Pierre
Scholler, Nathalie
Dranoff, Glenn
Gelfand, Jeffrey
Poznansky, Mark C.
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7
[2] MTBhsp70 fusion protein targeting mesothelin augments tumor specific T cell responses and prolongs survival in a murine model of ovarian cancer
Yuan, Jianping
Leblanc, Pierre
Kashiwagi, Satoshi
Nezivar, Jean
Righi, Elda
Santosuosso, Michael
Korochkina, Svetlana
Orsulic, Sandra
Scholler, Nathalie
Dranoff, Glenn
Gelfand, Jeffrey
Poznansky, Mark
CANCER RESEARCH, 2012, 72
[3] Combination of mesothelin-targeted immune-activating fusion protein and anti-PD-L1 augments antitumor immunity and prolongs survival in murine model of ovarian cancer
Zeng, Yang
Li, Binghao
Liu, Qiuyan
Reeves, Patrick
Sluder, Ann
Gelfand, Jeffrey
Brauns, Timothy
Poznansky, Mark
Chen, Huabiao
CANCER RESEARCH, 2017, 77
[4] Could mycobacterial Hsp70-containing fusion protein lead the way to an affordable therapeutic cancer vaccine?
Brauns, Timothy
Leblanc, Pierre
Gelfand, Jeffrey A.
Poznanski, Mark
EXPERT REVIEW OF VACCINES, 2015, 14 (03) : 435 - 446

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