Exosomes as Carriers for Drug Delivery in Cancer Therapy

被引：0
|
作者：
Weiping Zeng
Zhengbo Wen
Honglin Chen
Yuyou Duan
机构：
[1] South China University of Technology,School of Biology and Biological Engineering
[2] South China University of Technology,Laboratory of Stem Cells and Translational Medicine, Institutes for Life Sciences, School of Medicine
[3] South China University of Technology,National Engineering Research Center for Tissue Restoration and Reconstruction
[4] South China University of Technology,Guangdong Provincial Key Laboratory of Biomedical Engineering
[5] South China University of Technology,Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education
来源：
Pharmaceutical Research | 2023年 / 40卷
关键词：
Cancer therapy; Drug delivery; Extracellular vesicles; Exosomes;
D O I：
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中图分类号：
学科分类号：
摘要：
Exosomes are extracellular vesicles secreted by cells with a particle size of 30–150 nm in diameter. Exosomes can be used as natural drug carriers. The treatment of cancer with drug-loaded exosomes is an area of high interest. This review introduces the composition, function, isolation and characterization of exosomes, and briefly describes the selection of exosome donor cells and methods for drug loading. Through studies on therapies with drug-loaded exosomes in gastric cancer, lung cancer, brain cancer and other cancers, the advantages and disadvantages of drug-loaded exosomes have been analyzed.
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页码：873 / 887
页数：14
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