Basic mechanisms of antiepileptic drugs and their pharmacokinetic/pharmacodynamic interactions: an update

被引：0
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作者：
Władysław Lasoń
Monika Dudra-Jastrzębska
Konrad Rejdak
Stanisław J. Czuczwar
机构：
[1] Polish Academy of Sciences,Department of Experimental Neuroendocrinology
[2] Jagiellonian University,Department of Drug Management, Institute of Public Health
[3] Medical College,Department of Pathophysiology
[4] Medical University of Lublin,Department of Neurology
[5] Medical University of Lublin,Department of Physiopathology
[6] Institute of Agricultural Medicine,undefined
来源：
Pharmacological Reports | 2011年 / 63卷
关键词：
antiepileptic drugs; epilepsy; drug interactions; seizures;
D O I：
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学科分类号：
摘要：
This article aims to summarize the current views of AED action and the promising new targets for the pharmacotherapy of epilepsy. In the first section of this paper, a neurobiological basis of epilepsy treatment and brief pharmacological characteristics of classical and new AEDs will be presented. In the second part, the results of experimental studies that have combined AEDs with similar or different mechanisms of action will be discussed.
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页码：271 / 292
页数：21
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