Effects of hypoxanthine at low concentrations on in vitro maturation and fertilization of bovine oocytes

被引：0
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作者：
I. G. Smetanina
L. V. Tatarinova
A. S. Krivokharchenko
机构：
[1] Biochemistry,All
[2] and Nutrition,Russia Research Institute of Animal Physiology
[3] Russian Academy of Sciences,Semenov Institute of Chemical Physics
来源：
Biology Bulletin | 2017年 / 44卷
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摘要：
The effects of hypoxanthine (HX) at low concentrations on the ability of bovine oocyte to mature to metaphase 2 (M2) and to fertilize in vitro have been studied. It is proved that exogenous HX even at a low concentration, which was introduced into the HX-free and protein-free alpha-MEM medium supplemented with 1 μg/mL follicle-stimulating hormone, can significantly decrease the proportions of both the oocytes the matured to stage M2 and the penetrated and normally fertilized oocytes. It is indicated that the data may be used in order to develop commercial media for in vitro maturation of oocytes of mammalia, including humans.
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页码：477 / 480
页数：3
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